DrugInfoSys

Rho (D) Immune Globulin

Drug #995

Rho (D) Immune Globulin is a sterile solution of globulins derived from human plasma containing antibody to the erythrocyte factor Rh? (D) antigen. Rho (D) Immune Globulin is used to prevent a Rh-negative mother from forming antibodies to fetal Rh-positive cells which may pass into the maternal circulation. The objective is to protect any subsequent child from the hazard of the haemolytic disease of the newborn. Anti-D immunoglobulin should be administered following any sensitizing episode e.g abortion, miscarriage and birth.

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Primary Characteristics

It belongs to Globulins.

It is classified in Immune Globulin pharmacological group.

Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Rho (D) Immune Globulin.

Molecular structure of Rho (D) Immune Globulin

Pharmacokinetics

Elimination: plasma half-life is 24 days.

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Indications

Rho (D) Immune Globulin is primarily indicated in conditions like Erythroblastosis fetalis, Immune thrombocytopenic purpura, Rhesus blood mismatch.

Contraindications

Rho (D) Immune Globulin is contraindicated in conditions like Anaphylactic reactions, Hypersensitivity to any component of product.

Dosage

Rho (D) Immune Globulin 's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
300 ug300 ugEvery 24hIMGive within 72 Hours of fullterm delivery of an Rho (D) Positive infant. Incidence can be further reduced by giving two doses, one at 28 weeks gestation, one following delivery
Paediatric Dosage (20kg)
0 – 0——Not recommended in this age group
Neonatal Dosage (3kg)
0 – 0——Not recommended in this age group

Drug Interactions

Moderate5 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Rho (D) Immune Globulin in overdosage may give rise to further complications which include Spleenomegaly .

Rho (D) Immune Globulin is known to cause more or less tolerable side effects which are usually transient. These include Chills, Fever, Headache, Hyperthermia , Lethargy, Local pain, Myalgia, Splenomegaly .

Warnings / Precautions

Immune globulin should be used with caution in patients with any pre-existing illness, blood disorders or any allergy, including any drug allergy. It should be used only when clearly needed during pregnancy.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Inj
300 mcg50 mcg

Storage Conditions

Rho (D) Immune Globulin should be stored Inj.

Drug Classification

  1. 1.19.2.1 — Anti-D immunoglobulins (human)

Manufacturers

Manufacturers of Rho (D) Immune Globulin in Pakistan:

AmsonETDCHakimsonsIBLPopular Int.