Propyphenazone
Propyphenazone is analgesic and antipyretic agent. Propyphenazone is given by mouth or rectally in the treatment of pain and fever.
Primary Characteristics
It is of Synthetic origin and belongs to Pyrazolone.
It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action. It is also classified under Analgesics and Anti-inflammatory Agents .
Molecular Weight: 230.3 · Solubility in Water: slightly soluble · Solubility in Alcohol: freely soluble · Non-proprietary name: Propyphenazone.
Pharmacokinetics
Elimination: renal excretion is 0.6 % (unchanged).
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Indications
Contraindications
Propyphenazone is contraindicated in conditions like Porphyrias.
Dosage
Propyphenazone's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 112.5 mg | 112.5 mg | Every 12h | PO | |
| Paediatric Dosage (20kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Propyphenazone is known to cause more or less tolerable side effects which are usually transient. These include Dizziness, Headache, Nausea, Tiredness .
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.2.1.3 — Non steroidal anti-inflammatory drugs (NSAIDs)