Povidone-Iodine

Drug #977

Povidone-Iodine is used as a pre-operative skin antiseptic. It is itused as a component in arteficial tears and contac lens solutions.

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Primary Characteristics

It is of Synthetic origin.

It is also classified under Antiseptics and Germicides .

Solubility in Water: soluble · Solubility in Alcohol: soluble · Non-proprietary name: Povidone-Iodine · pH: 1.5.

Pharmacokinetics

None recorded.

Indications

Povidone-Iodine is primarily indicated in conditions like Contaminated wounds, Pre-operative skin preparation, Superficial infections.

Contraindications

Povidone-Iodine is contraindicated in conditions like Renal failure, Pregnancy, Neonates, Hypersensitivity to any component of product.

Dosage

Povidone-Iodine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
10 %	10 %	Every 4h	Gargle
0.6 %	0.6 %	—	Ophthalmic	As required
0.1 %	0.1 %	—	Topical	Mouth wash.
Paediatric Dosage (20kg)
0 – 0	—	—		SA
Neonatal Dosage (3kg)
No data.

Drug Interactions

2 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Povidone-Iodine in overdosage may give rise to further complications which include Renal impairment , Hypernatremia, Hypersensitivity reactions , Hyperthyroidism , Metabolic acidosis , Iododerma .

Povidone-Iodine is known to cause more or less tolerable side effects which are usually transient. These include Local edema, Mucous membrane irritation, Pruritus , Rashes , Skin irritation.

Warnings / Precautions

Highly toxic if ingested, sodium thiosulfate is the most effective chemical antidote, avoid contact with eyes. Regular or prolonged use should be avoided in patient with thyroid disorders or those receiving lithium therapy.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Gel

0.5 %w/w 10 %10 %w/w 5 %w/w

Liquid

0.1 %w/v

Mouth Wash

1 %w/v

Powder

0.5 %w/w

Scrub

0.1 %w/w 7.5 %w/v 7.5 %w/w 7.5 gm

Soln

1 %w/v 10 %w/v 10 g/100ml 50 mg

Soln

7.5 %w/v

Multi-Ingredient Combinations

Eye Drops

0.6 %w/v

Storage Conditions

Povidone-Iodine should be stored Soln.

Drug Classification

1.15 — Disinfectants and antiseptics
2.17.8 — Stomatologicals and dentifrices
3.25.5 — Pharyngeal preparations

Manufacturers

Manufacturers of Povidone-Iodine in Pakistan:

Abbott Barrett Baxter Brookes Eros Everest Global Hoover Indus Irza KCI Kobec Kohinoor Lahore Pharma LCPW Mediate Medisearch Mendoza Nawabsons Labs Ophth-Pharma Pharmawise Prime Rehmat Sante Sapient Spencer Trigon Valor