Piribedil
Piribedil is non-ergot dopamine agonist. It is given by mouth in the treatment of parkinsonism and in circulatory disorders. The mesylate salt has been given by injection for similar indications.
Primary Characteristics
It belongs to Pyrimidine.
It is classified in Cerebral & Peripheral, Dopamine Rec Stimulator pharmacological group. It is also classified under Psychotherapeutic Drugs .
Molecular Weight: 298.3 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Piribedil.
Pharmacokinetics
Elimination: plasma half-life is 1.7-6.9 hrs, renal excretion is 68%.
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Indications
Piribedil is primarily indicated in conditions like Dizziness, Parkinsonism, Retinal ischaemic manifestations.
Contraindications
None recorded.
Dosage
Piribedil's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 125 mg | 125 mg | Every 24h | PO | |
| Paediatric Dosage (20kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
| Neonatal Dosage (3kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Piribedil is known to cause more or less tolerable side effects which are usually transient. These include Drowsiness, Flatulence, Nausea and vomiting.
Warnings / Precautions
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.9.1 — Drugs used in parkinsonism
Manufacturers
Manufacturers of Piribedil in Pakistan: