Pirenoxine - Drug Monograph | DrugInfoSys ODIS

Primary Characteristics

It is of origin and belongs to Pyrido Phenoxazine .

It is classified in Anticataract pharmacological group. It is also classified under Opthalmic Products .

Molecular Weight: 3302 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Pirenoxine.

Pharmacokinetics

Distribution: Pirenoxine has a volume of distribution is . plasma protein binding is .

Elimination: it is metabolised via , plasma half-life is , renal excretion is .

Indications

Pirenoxine is primarily indicated in conditions like Cataract, Induction of labour, Inevitable abortion, Labor augmentation, Lactation induction, Postpartum haemorrhage, Uterine atonia.

Contraindications

Pirenoxine is contraindicated in conditions like Uterine hyperactivity, Placenta previa.

Dosage

Pirenoxine's dosage details are as follows:

Dose	Single Dose	Frequency	Route
Adult Dosage
1125 ug	1125 ug	Every 4.8h	Ophthalmic
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Pirenoxine in overdosage may give rise to further complications which include Conjunctival infections, Marginalis , Keratitis , Smarting .

Pirenoxine is known to cause more or less tolerable side effects which are usually transient. These include Blepharitis , Itching.

Warnings / Precautions

Use only by instillation, store the ophthalmic solution, once prepared, protects from heat, light and moisture and use within 20 days. Avoid contact of the tip of dropper with eye when instilling. This drug changes colour in the presence of metallic ion.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Eye Drops

0.75 mg

Storage Conditions

Pirenoxine should be stored Eye drops.

Drug Classification

1.21.7 — Other ophthalmologicals

Manufacturers

Manufacturers of Pirenoxine in Pakistan:

Helix