Biotin
Biotin is a water soluble dicyclic monocarboxylic acid considered to be part of vitamin B complex. Biotin is essential cofactor for several carboxylases, plays a role in the metabolism of fatty acids and the deamination of certain amino acids. Deficiencies in humans have occured only after prolonged total parentral nutrition not supplemented with it or on ingestion of large quantities of raw egg whites.
Primary Characteristics
It is of Natural origin and belongs to Imidazole.
It belongs to Nutrients and Vitamins pharmacological group on the basis of mechanism of action.
Molecular Weight: 244.3 · Solubility in Water: 1 in 5000 · Solubility in Alcohol: 1 in 1000 · Non-proprietary name: Biotin.
Pharmacokinetics
Absorption: Biotin has an oral bioavailability is 77.5% (±2.5%).
Distribution: Biotin has a plasma protein binding is extensive.
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Indications
Biotin is primarily indicated in conditions like Dietry biotin deficiency, Multiple carboxylase deficiency.
Contraindications
Biotin is contraindicated in conditions like Hypersensitivity to any component of product.
Dosage
Biotin's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 105 mcg | 105 mcg | Every 24h | PO | For 3 Months |
| Paediatric Dosage (20kg) | ||||
| 4 mg/kg | 4 mg/kg | Every 24h | Oral | For several months |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
None recorded.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.27 — Vitamins, minerals, tonics, and other susbstances