Meclozine
Also known as: Meclizine HCL
Meclozine is a sedating anti-histamine with anti-muscarinic properties. Meclozine is mainly used in the prevention and treatment of nausea and vomitting, and for symptomatic treatment of vertigo, hypersensitivity reactions and pruritic skin disorders.
Primary Characteristics
Meclozine is also known as Meclizine HCL.
It belongs to Piperazine.
Molecular Weight: 390.95 · Non-proprietary name: Meclozine.

Pharmacokinetics
Elimination: it is metabolised via hepatic, plasma half-life is 6 hr.
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Indications
Meclozine is primarily indicated in conditions like Emesis, Motion sickness, Nausea and vomiting, Vertigo, Vestibular disturbances.
Contraindications
None recorded.
Dosage
Meclozine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 37.5 mg | 37.5 mg | Every 8h | Oral | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Meclozine in overdosage may give rise to further complications which include Tachycardia , Seizures , Irregular heart beat, Tachycardia.
The signs and symptoms that are produced after acute overdosage of Meclozine are Nausea & vomiting.
Meclozine is known to cause more or less tolerable side effects which are usually transient. These include Allergic rashes, Allergic skin reactions, Diarrhea, Dizziness, Dry mouth, Tiredness .
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.17.2 — Antiemetics & antinauseants