Cyclodextrin
Cyclodextrin used as a carrier molecules for drug delivery systems.
Primary Characteristics
It is of Synthetic origin.
It is classified in Prostaglandin pharmacological group.
Solubility in Water: sparingly · Solubility in Alcohol: insoluble · Non-proprietary name: Cyclodextrin.
Pharmacokinetics
None recorded.
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Indications
Cyclodextrin is primarily indicated in conditions like Chronic occlusive arterial disease.
Contraindications
Cyclodextrin is contraindicated in conditions like Pulmonary edema.
Dosage
Cyclodextrin's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.153 mg/kg.min | 0.153 mg/kg.min | — | IV Inf | For 180 minutes, every 2-3 weeks |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| 0.075 ug/kg/min | 0.075 ug/kg/min | — | Infusion | Initial |
| 0.205 ug/kg/min | 0.205 ug/kg/min | — | Infusion | Maintenance, As required |
Drug Interactions
None recorded.
Side Effects
Cyclodextrin is known to cause more or less tolerable side effects which are usually transient. These include Diarrhea, Hepatotoxicity, Liver dysfunction, stomach cramping.
Warnings / Precautions
Interference in Pathology
Cyclodextrin may interfere in the diagnosis of Liver Function Test (LFT) .
Available Brands
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Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.99 — Unassigned
Manufacturers
Manufacturers of Cyclodextrin in Pakistan: