Cyclopentolate (HCl)

Drug #871

Cyclopentolate (HCl) is antimuscarinic agent and used to dilate the pupil in opthalmology with more rapid onset and shorter duration.

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Primary Characteristics

It is of Synthetic origin and belongs to Phenyl Acetate.

It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action. It is also classified under Opthalmic Products .

Molecular Weight: 327.8 · Solubility in Water: very soluble · Solubility in Alcohol: freely soluble · Non-proprietary name: Cyclopentolate (HCl).

Molecular structure of Cyclopentolate (HCl)

Pharmacokinetics

None recorded.

Indications

Cyclopentolate (HCl) is primarily indicated in conditions like Diagnostic aid for mydriasis and cycloplegia.

Contraindications

Cyclopentolate (HCl) is contraindicated in conditions like Narrow-angle glaucoma.

Dosage

Cyclopentolate (HCl)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
0.5 mg	0.5 mg	—	Ophthalmic	Repeated after 5 min
1 %	1 %	—	Ophthalmic	Repeated after 5 minutes.
Paediatric Dosage (20kg)
0.5 mg	0.5 mg	—	Opthalmic	Once or repeated in 5min as required
Neonatal Dosage (3kg)
0.5 mg	0.5 mg	—	Opthalmic	Once or repeated in 5min as required

Drug Interactions

Unknown1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Cyclopentolate (HCl) in overdosage may give rise to further complications which include Convulsions , Disturbance of speech .

Cyclopentolate (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Allergic reactions, Ataxia, Burning sensation, Hallucination , Hyperactivity, Increased IOP , Loss of accomodation, Psychosis, Restlessness, Vision disturbances.

Warnings / Precautions

It should be used with caution in elderly patients and other patients who may be predisposed to increased intraocular pressure, hypersensitivity to belladonna alkaloids, synechiae, Downs syndrome. Cyclopentolate 2% solution may result in psychotic reactions and behavioral disturbances in children, usually occurring approximately 30-45 minutes after instillation. It is classified as pregnancy category C and should be used with caution during pregnancy only if clearly needed.

Available Brands

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Single Ingredient

Eye Drops

1 %w/v

Storage Conditions

Cyclopentolate (HCl) should be stored Eye Drops.

Drug Classification

1.21.5 — Mydriatics, Cycloplegics

Manufacturers

Manufacturers of Cyclopentolate (HCl) in Pakistan:

Ethical Novartis