Citicoline
Also known as: CDP-Choline, Citidoline, Cytidine Diphosphate choline
Citicoline (Na) increases the blood flow in brain and used in the treatment of cerbro-vascular disorders such as ischaemic stroke and head injury.
Primary Characteristics
Citicoline is also known as CDP-Choline, Citidoline, Cytidine Diphosphate choline, Citicoline (Na).
It is of Synthetic origin and belongs to Choline Cytidine.
It is also classified under Psychotherapeutic Drugs .
Molecular Weight: 488.3 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Citicoline.
Pharmacokinetics
Elimination: it is metabolised via Hepatic, plasma half-life is 24 hr.
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Indications
Citicoline is primarily indicated in conditions like Cardiac stroke, Head trauma, Ischaemic heart disease, Paralysis of lower extremities.
Citicoline is also indicated for secondary conditions like Parkinson's disease.
Contraindications
Citicoline is contraindicated in conditions like Unconciousness, Brain surgery, Pregnancy, Breast feeding.
Dosage
Citicoline's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1 g | 1 g | Every 24h | IV | For 4 weeks. |
| 200 – 600 mg | — | — | PO | Total dose can be given as 2 divided doses. For 6 weeks. |
| Paediatric Dosage (20kg) | ||||
| 0 – 0 | — | — | — | Not Recommended in this Age Group |
| Neonatal Dosage (3kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
Drug Interactions
None recorded.
Side Effects
Citicoline in overdosage may give rise to further complications which include Hypotension .
Citicoline is known to cause more or less tolerable side effects which are usually transient. These include Excitement, Insomnia.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.24.5 — Psychostimulants, nootropics, and neurotonics