Sucralfate
Sucralfate is aluminium-sucrose complex, is a sulphated disaccharide developed for the treatment of peptic ulcer. It protects layer on gastro-duodenal mucosa by forming a complex with pepsin which adhere to active ulcers.
Primary Characteristics
It is of Synthetic origin and belongs to Glucofructose.
It is classified in Ulcer Healing pharmacological group. It is also classified under Antacids .
Non-proprietary name: Sucralfate.
Pharmacokinetics
None recorded.
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Indications
Sucralfate is primarily indicated in conditions like Benign gastric and duodenal ulceration and chronic gastritis, Duodenal ulcer, Peptic ulcer, Prophylaxis of stress ulceration, Reflux oesophagitis.
Sucralfate is also indicated for secondary conditions like Benign gastric and duodenal ulceration, Inflammatory bowel disease.
Contraindications
None recorded.
Dosage
Sucralfate's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1 g | 1 g | Every 6h | PO | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| 0 – 0 | — | — | Safety not established | |
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Sucralfate is known to cause more or less tolerable side effects which are usually transient. These include Constipation .
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.17.1.2 — Anti-peptic ulcerants
Manufacturers
Manufacturers of Sucralfate in Pakistan: