Sodium Calciumedetate

Also known as: Calcium-EDTA, Edetate Calcium disodium, Sodium Calcium edetate

Drug #661

Sodium Calciumedetate is a chelating agent. Sodium Calciumedetate is used in the treatment of lead poisoning.

Primary Characteristics

Sodium Calciumedetate is also known as Calcium-EDTA, Edetate Calcium disodium, Sodium Calcium edetate.

It is of Synthetic origin and belongs to Chelating Agent.

It is classified in Chelating Agent pharmacological group.

Molecular Weight: 410.3 · Solubility in Water: 1 in 2 · Solubility in Alcohol: almost insoluble · Non-proprietary name: Sodium Calciumedetate · pH: 6.1 · Isotonic value: 4.5.

Molecular structure of Sodium Calciumedetate

Pharmacokinetics

Absorption: Sodium Calciumedetate has an oral bioavailability is 5.5% (±4.5%).

Elimination: plasma half-life is 20 - 60 min.

Indications

Sodium Calciumedetate is primarily indicated in conditions like Lead poisoning, Skin diseases.

Contraindications

Sodium Calciumedetate is contraindicated in conditions like Renal insufficiency.

Dosage

Sodium Calciumedetate's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
14.29 mg/kg.hr	14.29 mg/kg.hr	Every 12h	IV Inf	Upto 2.1-2.8 Hours for 5 Days
Paediatric Dosage (20kg)
40 mg/kg	40 mg/kg	Every 12h	IV Infusion	Treat for up to 5 days
Neonatal Dosage (3kg)
40 mg/kg	40 mg/kg	Every 12h	IV Infusion	Treat up to 5 days

Drug Interactions

Unknown1 interaction

7 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Sodium Calciumedetate in overdosage may give rise to further complications which include Renal tubular changes .

Sodium Calciumedetate is known to cause more or less tolerable side effects which are usually transient. These include Fatigue, Headache, Malaise, Nausea and vomiting, Thirst, Urinary frequency, Urinary urgency.

Warnings / Precautions

Sodium calciumedetate should be used with caution in patients with impaired renal function. Regular monitoring of renal function for proteinuria and haematuria has been recommended. It should not be given by mouth in the treatment of lead poisoning.

Interference in Pathology

Sodium Calciumedetate may interfere in the diagnosis of Urinanalysis , Serum test for Creatinine and Glucose , Monitoring of Serum phosphate levels.

Available Brands

None recorded.

Storage Conditions

Sodium Calciumedetate should be stored Inj.

Drug Classification

1.4.2.5 — Lead poisoning