Phenol
Also known as: Carbolic acid, Fenol, Phenolum, Phenyl hydrate
Phenol is used as a caustic, disinfectant, fungicide and topical anesthetic. italso commonly employed as an anti-pruritic and also as a preservative for injections.
Primary Characteristics
Phenol is also known as Carbolic acid, Fenol, Phenolum, Phenyl hydrate.
It is of Natural origin and belongs to Phenol.
It belongs to Dermatological-Caustic pharmacological group on the basis of mechanism of action. It is also classified under Dermatological Products .
Molecular Weight: 94.1 · pKa: 10.0 · Solubility in Water: 1 in 15 · Solubility in Alcohol: very soluble · Non-proprietary name: Phenol · pH: 5.6 · Isotonic value: 2.8.
Pharmacokinetics
None recorded.
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Indications
Phenol is primarily indicated in conditions like Pain, Pruritus, Sclerosing agent, Sepsis.
Contraindications
Phenol is contraindicated in conditions like Occlusion.
Dosage
Phenol's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.75 % | 0.75 % | — | Topical | As Required |
| Paediatric Dosage (20kg) | ||||
| 0 – 0 | — | — | Not recommended for this age group | |
| Neonatal Dosage (3kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
Drug Interactions
None recorded.
Side Effects
Phenol in overdosage may give rise to further complications which include Poisoning .
Phenol produces potentially life-threatening effects which include Coma, Cyanosis, Abdominal pain, Dizziness, Methemoglobinemia, Hemoglobinuria. Careful monitoring is needed with proper medical management.
The signs and symptoms that are produced after acute overdosage of Phenol are Vomiting, Pulmonary edema , Shock, Respiratory failure, Local pain.
Phenol is known to cause more or less tolerable side effects which are usually transient. These include Collapse, Darkening of corners, Darkening of facial skin, Dizziness, Exogenous ochronosis.
Warnings / Precautions
Interference in Pathology
Phenol may interfere in the diagnosis of Tri-OH-indole method of estimating plasma adrenaline and noradrenaline , Ferric Chloride test for ketones or salicylates in urine , Measurement of Sulphonamides in serum , Benedict's Test for Glycosuria , Test for ionized calcium in serum .
Available Brands
Storage Conditions
Drug Classification
- 1.13.3.3 — Antipruritics