Peritoneal Dialysis Fluids

Drug #555

Peritoneal Dialysis Fluidsused in dialysis procedures, which are used as a part of renal replacement therapy in renal fialure to correct electrolye imbalance, correct fluid overload and remove metabolite.

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Primary Characteristics

It is of Natural origin and belongs to Electrolytes .

It is classified in Dialysis Solutions pharmacological group.

pK_a: · Solubility in Water: · Solubility in Alcohol: · Non-proprietary name: Peritoneal dialysis fluids.

Molecular structure of Peritoneal Dialysis Fluids

Pharmacokinetics

Distribution: Peritoneal Dialysis Fluids has a volume of distribution is . plasma protein binding is .

Elimination: it is metabolised via Hepatic , plasma half-life is , renal excretion is .

Indications

Peritoneal Dialysis Fluids is primarily indicated in conditions like Hypothermia, Pancreatitis, Poisoning, Renal failure.

Contraindications

Peritoneal Dialysis Fluids is contraindicated in conditions like Respiratory disease.

Dosage

Peritoneal Dialysis Fluids's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
17.856 ml/kg	17.856 ml/kg	—	Intra Peritoneal	Over 10 Minutes per hour, As Required
Paediatric Dosage (20kg)
30 ml/kg.hr	30 ml/kg.hr	—	Intra Peritoneally	As Required
Neonatal Dosage (3kg)
30 ml/kg.hr	30 ml/kg.hr	—	Intra Peritoneally	As Required

Drug Interactions

None recorded.

Side Effects

Peritoneal Dialysis Fluids in overdosage may give rise to further complications which include Hyperlipidemia, Hyperglycemia , Hyperproteinemia.

Peritoneal Dialysis Fluids produces potentially life-threatening effects which include Hypokalemia, Hypovolemia, Hypernatremia. Careful monitoring is needed with proper medical management.

Peritoneal Dialysis Fluids is known to cause more or less tolerable side effects which are usually transient. These include Bleeding , Catheter blockage, Ileus, Pain , Peritonitis.

Warnings / Precautions

Peritoneal dialysis should be done with great care, if at all, in patients with a number of abdominal conditions including disruption of the peritoneal membrane or diaphragm by surgery or trauma, extensive adhesions, bowel distention, undiagnosed abdominal disease, abdominal wall infection, hernias or burns, fecal fistula or colostomy, tense ascites, obesity, and large polycystic kidneys. An accurate fluid balance record must be kept and the weight of the patient carefully monitored to avoid over or under hydration with severe consequences including congestive heart failure, volume depletion, and shock. In acute renal failure patients, plasma electrolyte concentrations should be monitored periodically during the procedure.

Available Brands

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Single Ingredient

Inf

1.5 %w/v 2.3 %w/v 4.25 %w/v

Mouth Wash

0.25 %w/v

Storage Conditions

Peritoneal Dialysis Fluids should be stored Soln.

Drug Classification

1.23 — Peritoneal dialysis solution

Manufacturers

Manufacturers of Peritoneal Dialysis Fluids in Pakistan:

Platinum RG