Noxythiolin
Noxythiolin is anti-infective, with antibacterial and antifungal activity. It is used to prevent and treat infection in bladder after bladder operation.
Primary Characteristics
It is of Synthetic origin and belongs to Thiourea.
It belongs to Dermatological-Antiseptic pharmacological group on the basis of mechanism of action. It is also classified under Antiseptics and Germicides .
Molecular Weight: 120.2 · pKa: not relevant · Solubility in Water: 1 in 10 · Solubility in Alcohol: 1 in 25 · Non-proprietary name: Noxythiolin.
Pharmacokinetics
None recorded.
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Indications
Noxythiolin is primarily indicated in conditions like Bladder infections, Dental infections, Fistulae, Infected wounds, Peritoneal infections.
Contraindications
None recorded.
Dosage
Noxythiolin's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1 – 2.5 % | — | — | Intra Peritoneal | For 3 to 7 days, as required |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| 1 % | 1 % | — | Intrapritoneal | As required |
Drug Interactions
None recorded.
Side Effects
Noxythiolin in overdosage may give rise to further complications which include Anorexia , Bleeding , Malaise .
Noxythiolin is known to cause more or less tolerable side effects which are usually transient. These include Anorexia , Burning sensation, Fetid breath, Large fibrin clumps, Nausea.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.15 — Disinfectants and antiseptics