Nicotinamide

Also known as: Niacinamide

Drug #511

Nicotinamide is the active form of niacin ( vitamin B 3 ), niacine is a water soluble vitamin, used in multivitamin preparations. It posses antinflammatory properties. it is used topically in the treatment of acne. it is also used to lower blood cholesterol and fat levels.

← Previous drug Next drug →

Primary Characteristics

Nicotinamide is also known as Niacinamide, Nicotinamide areorbate.

It is of Natural origin and belongs to Amide.

It is classified in Vitamin, Water Soluble pharmacological group.

Molecular Weight: 122.1 · Solubility in Water: 1 in 1 · Solubility in Alcohol: 1 in 1.5 · Non-proprietary name: Nicotinamide · pH: 7 · Isotonic value: 4.49.

Pharmacokinetics

Elimination: it is metabolised via Hepatic.

Indications

Nicotinamide is primarily indicated in conditions like Hartnup disease, Inflammatory skin disease, Vitamin deficiency.

Contraindications

Nicotinamide is contraindicated in conditions like Wilson's disease, Hypersensitivity to any component of product.

Dosage

Nicotinamide's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
2.499 mg/kg	2.499 mg/kg	Every 24h	IV	-
50 mg	50 mg	Every 8h	PO	Frequency may be increased upto 10 times/day if needed.
Paediatric Dosage (20kg)
1 mg/kg	1 mg/kg	Every 24h	Oral	-
Neonatal Dosage (3kg)
0.937 mg/kg	0.937 mg/kg	Every 24h	Oral

Drug Interactions

Unknown3 interactions

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Nicotinamide produces potentially life-threatening effects which include Hepatotoxicity , Cholestasis , Portal fibrosis. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Nicotinamide are Transient liver dysfunctioning.

Nicotinamide is known to cause more or less tolerable side effects which are usually transient. These include Chills, Dry hair, Dypnoea, Faintness , Fatigue, Flushing, Headache, Heart burn, Inability of eye focusing, Nausea, Oedema, Palpitation, Sensation of Heat, Sore throat, Sweating , Tachycardia, Tautness of the Face .

Warnings / Precautions

Nicotinamide should be used with caution in patients with history of heart disease, high blood pressure or insulin-dependent diabetes. This is not recommended for use during pregnancy or lactation.

Available Brands

Click on a strength to view available brands.

Multi-Ingredient Combinations

Caps

10 mg 100 mg 15 mg 150 mg 18 mg 20 mg 24 mg 25 mg 30 mg 50 mg 9 mg

Caps

8.2 mg

Dragees

50 mg

Dragees

6 mg

Drops

10 mg/0.6ml 10 mg/ml 5 mg/0.6ml

Eye Drops

2 %w/v

Inf

100 mg/10ml 75 mg/ml

Inf

60 mg/L

Inj

10 mg/ml 100 mg/ml 4.1 mg/ml 40 mg/ml 60 mg/3ml 75 mg/ml

Liquid

Sachet

Soft Caps

Susp

Syrup

16.66 mg/5ml 18 mg/5ml 33.33 mg/5ml 6 mg/5ml 8 mg/5ml

Tabs

10 mg 100 mg 12 mg 13.5 mg 15 mg 18 mg 19 mg 20 mg 25 mg 30 mg 33.3 mg 50 mg 6 mg 7.5 mg

Tabs efr

50 mg

Storage Conditions

Nicotinamide should be stored Tab.

Drug Classification

1.27 — Vitamins, minerals, tonics, and other susbstances