Niclosamide
Niclosamide is anthelmintic agent. Niclosamide is a salicylamide derivative. Niclosamide is used in the treatment of tapeworm infections.
Primary Characteristics
It is of Natural origin and belongs to Salicylamide.
It is classified in Anthelmintics pharmacological group.
Molecular Weight: 327.1 · Solubility in Water: < 1 in 10000 · Solubility in Alcohol: 1 in 150 · Non-proprietary name: Niclosamide.
Pharmacokinetics
None recorded.
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Indications
Niclosamide is primarily indicated in conditions like Helminth infection, Tapeworm infection.
Contraindications
Niclosamide is contraindicated in conditions like Hypersensitivity to any component of product.
Dosage
Niclosamide's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 2000 mg | 2000 mg | — | PO | Single dose (once). |
| Paediatric Dosage (20kg) | ||||
| 100 mg/kg | 100 mg/kg | — | Oral | Sigle dose .For 2-6 yrs of Children |
| Neonatal Dosage (3kg) | ||||
| 62.5 mg/kg | 62.5 mg/kg | — | Oral | Single dose |
Drug Interactions
None recorded.
Side Effects
The signs and symptoms that are produced after acute overdosage of Niclosamide are Fever, Increased metabolism.
Niclosamide is known to cause more or less tolerable side effects which are usually transient. These include GI adverse effects, Light headedness, Pruritus .
Warnings / Precautions
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.6.1.1 — Intestinal anthelmintics