Amethocaine

Also known as: Tetracaine, Tetracainum

Drug #44

Amethocaine is a local anaesthetic (agent that causes loss of sensation). Amethocaine is used topically in opthalmology.Tetracain is about four times as protest.

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Primary Characteristics

Amethocaine is also known as Tetracaine, Tetracainum.

It is of Synthetic origin and belongs to Benzoic Acid Ester.

It belongs to Na-Channel Local Anesthetic antagonist pharmacological group on the basis of mechanism of action.

Molecular Weight: 264.4 · pK_a: 8.2 - 8.6 · Solubility in Water: Freely soluble · Solubility in Alcohol: Soluble · Non-proprietary name: Amethocaine.

Pharmacokinetics

Distribution: Amethocaine has a plasma protein binding is 85%.

Elimination: plasma half-life is very short.

Indications

Amethocaine is primarily indicated in conditions like Local anaesthesia, Local anaesthetic, Pruritus.

Contraindications

Amethocaine is contraindicated in conditions like Hypersensitivity to the drug.

Dosage

Amethocaine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
0 – 0	—	—
0 – 0	—	—
0.75 %	0.75 %	—	Ophthalmic	As Required
0.75 %	0.75 %	—	Ophthanln	As recommended for anaethesia of eye
Paediatric Dosage (20kg)
0 – 0	—	—	—	SA
Neonatal Dosage (3kg)
No data.

Drug Interactions

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Amethocaine in overdosage may give rise to further complications which include Allergy .

Amethocaine produces potentially life-threatening effects which include Convulsions , Inebriation, Tingling, Tinnitus, Nystagmus, Nausea, Vomiting, Twitching, Nystagmus , Numbness of tongue. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Amethocaine are Convulsions .

Warnings / Precautions

Amethocaine should not be applied to inflammed or highly vascular surface. It should not be used to provide anaesthesia for bronchoscopy or cystoscopy.Prolong application of anesthetic eye drops may damage the cornea.

Interference in Pathology

Amethocaine may interfere in the diagnosis of Proteins measurements in CSF .

Available Brands

None recorded.

Storage Conditions

Amethocaine should be stored Eye drops .

Drug Classification

1.1.2 — Local anesthetics