Malathion
Malathion widely used as a topical insecticide and ascaricide. itused in low conentration on skin for infestation of lice without producing systemic effects.
Primary Characteristics
It is of Synthetic origin and belongs to Organophosphate.
It belongs to Cholinestrase inhibitor pharmacological group on the basis of mechanism of action and also classified in Topical Solution pharmacological group.
Molecular Weight: 330.4 · Solubility in Water: Slightly soluble · Solubility in Alcohol: miscible · Non-proprietary name: Malathion.
Pharmacokinetics
Elimination: it is metabolised via Hepatic.
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Indications
Malathion is primarily indicated in conditions like Pediculosis, Scabies.
Contraindications
Malathion is contraindicated in conditions like Neonates, Hypersensitivity to any component of product.
Dosage
Malathion's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.5 % | 0.5 % | — | Topical | Apply as required |
| Paediatric Dosage (20kg) | ||||
| 0.5 % | 0.5 % | — | Topical | Apply as required |
| Neonatal Dosage (3kg) | ||||
| 0.5 % | 0.5 % | — | Topical | Apply as required |
Drug Interactions
None recorded.
Side Effects
Malathion produces potentially life-threatening effects which include Hepatic injury. Careful monitoring is needed with proper medical management.
The signs and symptoms that are produced after acute overdosage of Malathion are Nausea, Vomiting, Blurred vision, Abdominal pain.
Malathion is known to cause more or less tolerable side effects which are usually transient. These include Headache, Skin irritation.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.13.6 — Scabicides & pediculocides