DrugInfoSys

Ipecac

Also known as: Ipecacuanha

Drug #389

Ipecac is used as an expectorant. its larger doses are used for emergency treatment of ingested poison in children.

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Primary Characteristics

Ipecac is also known as Ipecacuanha.

It is of Natural origin and belongs to Alkaloid.

It belongs to Emetic (GI) pharmacological group on the basis of mechanism of action and also classified in Antidotes pharmacological group.

Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Ipecac.

Molecular structure of Ipecac

Pharmacokinetics

None recorded.

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Indications

Ipecac is primarily indicated in conditions like Acute oral drug overdose, Emesis induction in oral poisoning, Productive cough.

Contraindications

Ipecac is contraindicated in conditions like Unconciousness, Poisoning with corrosive agents, Ingestion of petroleum distillates, Ingestion of CNS stimulants, Antiemetic poisoning.

Dosage

Ipecac's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
1.4 mg1.4 mg—Productive cough
21 – 42 mg——POOnce or as required. may be repeated once only after 20 to 30 min.
Paediatric Dosage (20kg)
2.1 mg/kg2.1 mg/kg—Oral Once or repeated after 20 min, As Required
Neonatal Dosage (3kg)
1.312 mg/kg1.312 mg/kg—OralSingle dose may repeat after 20 min. if required

Drug Interactions

Unknown1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Ipecac in overdosage may give rise to further complications which include Diarrhoea , Hypotension , Proteinuria , Hypotension , Ventricular tachycardia , Dyspnea, Oedema , Persistent vomiting, Ventricular ectopics , Chest pain , ECG abnormalities, Atrial tachycardia, Proteinuria, proteinuria.

Ipecac produces potentially life-threatening effects which include Convulsions , Gastric damage, Mallory-weiss syndrome, Pneumomediastinum, Retropneumoperitoneum, Diaphragmatic rupture, Myopathy, Neuropathy , Diaphragmatic rupture, Aspiration pneumonia. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Ipecac are Bloody vomiting, GI hemorrhage, Bloodstained diarrhea, Circulatory collapse, Myocardial damage.

Ipecac is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Allergy , Diarrhea, Drowsiness, Lethargy.

Warnings / Precautions

Ipecac should not be used as an emetic in patients whose condition increases the risk of aspiration or patients in shocks. It is not recommended for use during pregnancy or lactation. Ipecac should not be adminsitered to a person who may be poisoned by hydrocarbon ingestion (Petroleum distillate), strong acid ingestion, or alkali ingestion, unless directed to do so. The drug should be used with extreme caution in the patient with strychnine toxicity or seizures, cardiac diseases or arteriosclerosis. If emesis does not occur, cardiovascular function can also be affected through systemic absorption of cardiotoxin contained in Ipecac, increases the risk in these patients.

Available Brands

Click on a strength to view available brands.

Multi-Ingredient Combinations

Syrup
0.0025 ml/5ml0.025 ml/5ml
Syrup
0.005 ml/5ml
Tabs
0.02 ml

Storage Conditions

Ipecac should be stored Syrup.

Drug Classification

  1. 1.4.1 — General care and non specific treatment
  2. 2.25.2.2 — Expectorants

Manufacturers

Manufacturers of Ipecac in Pakistan:

AbbottCCLDosacoHeliconIrzaMedicraftNovamed