DrugInfoSys

Hexachlorophane

Also known as: Hexachlorophene

Drug #355

Hexachlorophane is used as a topical antiseptic.

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Primary Characteristics

Hexachlorophane is also known as Hexachlorophene.

It is of Synthetic origin and belongs to Chlorophenol.

It belongs to Dermatological-Antiseptic pharmacological group on the basis of mechanism of action.

Molecular Weight: 406.9 · pKa: 5.7 · Solubility in Water: insoluble · Solubility in Alcohol: Freely soluble · Non-proprietary name: Hexachlorophane.

Molecular structure of Hexachlorophane

Pharmacokinetics

Elimination: it is metabolised via Hepatic, renal excretion is partial.

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Indications

Hexachlorophane is primarily indicated in conditions like Acne, Breast abscess, Disinfectant, Dislocation, Sepsis.

Contraindications

Hexachlorophane is contraindicated in conditions like Burns and scalds, Damage skin.

Dosage

Hexachlorophane's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
0.23 – 3 %——TopicalAs Required
Paediatric Dosage (20kg)
0.23 – 3 %——TopicalAs Required
Neonatal Dosage (3kg)
3 %3 %—Topical As Required

Drug Interactions

None recorded.

Side Effects

Hexachlorophane in overdosage may give rise to further complications which include Hyperbilirubinemia, Histological changes in CNS, Vacuolative myelinopathy .

Hexachlorophane produces potentially life-threatening effects which include Convulsions , Shock . Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Hexachlorophane are Death , Erythematous rash , Irritability, Anorexia , Sleepiness, General muscular contractions.

Hexachlorophane is known to cause more or less tolerable side effects which are usually transient. These include Abdominal cramps, Anorexia , Confusion, Dehydration , Nausea and vomiting, Photosensitivity, Rashes , Skin sensitization.

Warnings / Precautions

Don't apply on mucous membrane, burned & damaged skin + vagina . Don't use during pregnancy . Don't use in premature infanats.

Available Brands

None recorded.

Storage Conditions

Hexachlorophane should be stored Dusting powder, Cleansing emulsion, Liquid soap.

Drug Classification

  1. 1.15 — Disinfectants and antiseptics