Gramicidin
Gramicidin is antimicrobialcyclic palypetide. Gramicidin is used as local application to skin, wounds, burns and nose and mouth infections. & frequently used with a corticosteroid.
Primary Characteristics
It is of Natural origin and belongs to Polypeptide.
It belongs to Antibiotic (Cell Wall) pharmacological group on the basis of mechanism of action and also classified in Topical Skin Product pharmacological group.
Molecular Weight: 1141.4 · Solubility in Water: Insoluble · Solubility in Alcohol: sparingly soluble · Non-proprietary name: Gramicidin.
Pharmacokinetics
None recorded.
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Indications
Gramicidin is primarily indicated in conditions like Otitis externa, Superficial infections.
Contraindications
Gramicidin is contraindicated in conditions like Damage skin.
Dosage
Gramicidin's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.006 mg | 0.006 mg | Every 6h | Ear | - |
| 0.004 mg | 0.004 mg | Every 6h | Ophthalmic | - |
| 25 % | 25 % | Every 8h | Topical | - |
| Paediatric Dosage (20kg) | ||||
| 0.006 mg | 0.006 mg | Every 6h | Ear | |
| 0.004 mg | 0.004 mg | Every 6h | Opthalmic | - |
| 25 % | 25 % | Every 8h | Topical | - |
| Neonatal Dosage (3kg) | ||||
| 0.006 mg | 0.006 mg | Every 6h | Ear | - |
| 0.004 mg | 0.004 mg | Every 6h | Opthalmic | - |
| 25 % | 25 % | Every 8h | Topical | - |
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Gramicidin is known to cause more or less tolerable side effects which are usually transient. These include Irritation.
Warnings / Precautions
Available Brands
Click on a strength to view available brands.
Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.13.3.2 — Corticosteroids combinations
- 2.28 — Otic drugs