Framycetin (Sulphate)

Drug #328

Framycetin (Sulphate) is antibiotic and is used to treat a variety of bacterial infections including skin. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Framycetin (Sulphate) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.

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Primary Characteristics

It is of Natural origin and belongs to Neomycin.

It belongs to Antibacterial (Proetin synthesis inhibitor) pharmacological group on the basis of mechanism of action.

Molecular Weight: 712.28 · Solubility in Water: Freely Soluble · Solubility in Alcohol: very slight · Non-proprietary name: Framycetin (Sulphate).

Molecular structure of Framycetin (Sulphate)

Pharmacokinetics

Elimination: plasma half-life is 2-3 hrs.

Indications

Framycetin (Sulphate) is primarily indicated in conditions like Bacterial infections, Burns and scalds, Ear infection, Ent infections, Eye infections, GI infections, Infections of bladder, Skin infections, Surgical infections, Surgical leisions, Traumatic injury.

Framycetin (Sulphate) is also indicated for secondary conditions like Decontamination of digestive tract.

Contraindications

Framycetin (Sulphate) is contraindicated in conditions like Tuberculosis, Viral eye infection, Glaucoma.

Dosage

Framycetin (Sulphate)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
0.5 %	0.5 %	Every 4h	Topical	For infection of eye & ear skin infection
Paediatric Dosage (20kg)
0.5 %	0.5 %	Every 8h	Topical	As Required
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Framycetin (Sulphate) in overdosage may give rise to further complications which include Ototoxicity , GI symptoms, Posterior subcapsular cataract .

Framycetin (Sulphate) is known to cause more or less tolerable side effects which are usually transient. These include Burning sensation, Contact dermatitis, Inflammation, Irritation, Itching, pruritis(less commonly), Stinging.

Warnings / Precautions

It is recommended that you receive regular eye examinations while you taking this medicine, as it can sometimes cause eye problems. Consult your doctor if you experience any disturbances in your vision while taking this medicine.This medicine should not be used to treat a red eye not diagnosed by a doctor, as inappropriate use can cause blindness.Should be use with caution in children.This medicine is not to be taken by mouth. Prolong use may lead to adrenal suspenssion in infants.

Available Brands

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Multi-Ingredient Combinations

E and E Drops

0.3 %w/v

Storage Conditions

Framycetin (Sulphate) should be stored .

Drug Classification

1.21.1.1 — Antibacterials

Manufacturers

Manufacturers of Framycetin (Sulphate) in Pakistan:

Helix