Econazole (Nitrate)
Econazole (Nitrate) is a antifungal agent and is used to treat skin fungal infection.
Primary Characteristics
It is of Synthetic origin and belongs to Phenethyl imidazole.
It is classified in Antifungal Agent, Topical pharmacological group. It is also classified under Dermatological Products .
Molecular Weight: 444.7 · pKa: 6.6 · Solubility in Water: very slightly soluble · Solubility in Alcohol: slightly soluble · Non-proprietary name: Econazole (Nitrate).
Pharmacokinetics
Elimination: it is metabolised via hepatic, renal excretion is 40%.
Advertisement
Indications
Econazole (Nitrate) is primarily indicated in conditions like Cutaneous candidiasis, Fungal balanitis`, Fungal infection, Tinea infection, Vulvo-vaginal candidosis.
Econazole (Nitrate) is also indicated for secondary conditions like Pityriasis.
Contraindications
Econazole (Nitrate) is contraindicated in conditions like Allergy, Hypersensitivity to the drug.
Dosage
Econazole (Nitrate)'s dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 150 mg | 150 mg | — | Intravaginal | given at bed time.For 3 days .Apply to infection area twice a day. |
| 1 % | 1 % | — | Topical | Covered with dressing |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Econazole (Nitrate) is known to cause more or less tolerable side effects which are usually transient. These include Burning, Contact dermatitis, Erythema, Itching, Local irritation, Local sensitization, Porphyria, Pruritus , Stinging.
Warnings / Precautions
Interference in Pathology
Econazole (Nitrate) may interfere in the diagnosis of None well documented.
Available Brands
Storage Conditions
Drug Classification
- 1.13.3.2 — Corticosteroids combinations