Dipipanone (HCl)

Drug #252

Dipipanone (HCl) is analogue of mehadone. Dipipanone (HCl) is used as a narcotic analgesic and effective to relieve moderate to severe pain. Dipipanone (HCl) is administered subcutaneously, intramuscularly and intravenously.

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Primary Characteristics

It is of Synthetic origin and belongs to Opioid.

It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in Analgesic pharmacological group.

Molecular Weight: 404 · pK_a: 8.5 · Solubility in Water: 1 in 40 · Solubility in Alcohol: 1 in 1.5 · Non-proprietary name: Dipipanone (HCl).

Pharmacokinetics

Elimination: it is metabolised via Hepatic, plasma half-life is 20 hours, renal excretion is major.

Indications

Dipipanone (HCl) is primarily indicated in conditions like Moderate to severe pain.

Contraindications

Dipipanone (HCl) is contraindicated in conditions like Diabetes mellitus, Ulcerative colitis, Respiratory depression, Airway obstruction, Biliary spasm, Obstetric pain.

Dosage

Dipipanone (HCl)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
10 mg	10 mg	Every 6h	PO	Initially as Required
10 mg	10 mg	Every 6h	PO	May be increased in increaments of 5 mg.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown3 interactions

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Dipipanone (HCl) in overdosage may give rise to further complications which include Hypotension , Hypotension , Dependence , Agranulocytosis , Ischemic colitis, Generalized chorea, Hypersensitivity hepatitis.

Dipipanone (HCl) produces potentially life-threatening effects which include Respiratory depression. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Dipipanone (HCl) are Hypotension, Apnea, Respiratory depression, Miosis, Respiratory depression, Deepening coma, Pinpoint pupils, Circulatory failure, Respiratory depression.

Dipipanone (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Confusion, Constipation , Drowsiness, Euphoria, Facial flushing, Hallucination , Mood changes, Nausea, Paranoid delusions, Rashes , Restlessness, Sedation , Urticaria, Vertigo, Vomiting .

Warnings / Precautions

Dipipanone should be used with extreme caution in patients with hyperthyroidism, adrenocortical insufficiency, prostatic hypertrophy, hypotension secondary to hypovolumic shock, diabetes mellitus and phaeochromocytoma. The dose should be reduced in patients with impaired renal or hepatic function.

Available Brands

None recorded.

Storage Conditions

Dipipanone (HCl) should be stored Tab.

Drug Classification

1.2.2 — Opioid analgesics