Cetuximab
Cetuximab is used for: Treating certain types of head, neck, and colorectal cancer. This medicine may be used alone or along with radiation treatments or other medicines. It may also be used for other conditions as determined by your doctor
Primary Characteristics
Cetuximab is also known as Anti EGFr, Chemeric Monoclonal anti body.
It belongs to Chimeric Monoclonal antibody pharmacological group on the basis of mechanism of action.
Non-proprietary name: Cetuximab.
Pharmacokinetics
None recorded.
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Indications
Cetuximab is primarily indicated in conditions like Metastatic colorectal cancer, Squamous cell carcinoma of head, Squamous cell carcinoma of neck.
Contraindications
None recorded.
Dosage
Cetuximab's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 400 | 400 | — | IV infusion | Loading Dose Followed by 250 mg/metersq onve weekly (unit is mg/metersq ) |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Cetuximab produces potentially life-threatening effects which include Cardiopulmonary arrest, Hypomagnesemia, Hypotension/hypertension. Careful monitoring is needed with proper medical management.
Cetuximab is known to cause more or less tolerable side effects which are usually transient. These include Acneform rash, Anorexia , Asthenia , Constipation , Diarrhea, Dyspnea, Fever, Nausea, Skin reactions.
Warnings / Precautions
Available Brands
Click on a strength to view available brands.
Single Ingredient
Drug Classification
- 1.8.2 — Cytotoxic (anti-neoplastic) drugs
Manufacturers
Manufacturers of Cetuximab in Pakistan: