Deferiprone
Drug #2181
Deferiprone is an oral drug that chelates iron and is used to treat thalassaemia major.
Primary Characteristics
Molecular Weight: 139.15 · Non-proprietary name: Deferiprone.
Pharmacokinetics
Elimination: plasma half-life is 2-3hrs, renal excretion is 75-90%.
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Indications
Deferiprone is primarily indicated in conditions like Chronic iron overload, Thalassemia.
Contraindications
Deferiprone is contraindicated in conditions like Hypersensitivity to any component of product.
Dosage
Deferiprone's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 25 mg/kg | 25 mg/kg | Every 8h | PO | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Deferiprone is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Diarrhea, Joint pain.
Warnings / Precautions
Before taking deferiprone make sure your doctor or pharmacist knows:
If you are pregnant, trying for a baby or breast-feeding.
If you suffer from liver or kidney problems.
If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
If you have ever had an allergic reaction to this or any other medicine.
Available Brands
Drug Classification
- 1.4.2.4 — Iron poisoning and iron & aluminium overload