Nicotinyl Alcohol
Nicotinyl alcohol is a direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene.
Primary Characteristics
Molecular Weight: 109.1 · Solubility in Water: Freely soluble · Solubility in Alcohol: Sligthly soluble · Non-proprietary name: Nicotinyl Alcohol.
Pharmacokinetics
None recorded.
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Indications
Nicotinyl Alcohol is primarily indicated in conditions like Gangrene, Hyperlipidaemias, Menieres disease, Peripheral vasospasm, Vasospasm, Vertigo.
Contraindications
Nicotinyl Alcohol is contraindicated in conditions like Diabetes mellitus, Myocardial infarction, Peptic ulcer, Cerebrovascular disease, Glaucoma.
Dosage
Nicotinyl Alcohol's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 225 mg | 225 mg | — | PO | 2-3 times a day. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
The signs and symptoms that are produced after acute overdosage of Nicotinyl Alcohol are Fainting , Nausea & vomiting, Hypotension, Diarrhea, Hepatic toxicity, Dizziness, Rashes .
Nicotinyl Alcohol is known to cause more or less tolerable side effects which are usually transient. These include Flushing, Tingling , vasodialation.
Warnings / Precautions
Interference in Pathology
Nicotinyl Alcohol may interfere in the diagnosis of Elevations of SGPT and SGOT , Increased Alkaline Phosphatase Levels, Increased level of alanine aminotransferase.
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.12.3.7 — Direct vasodilators