Nilvadipine
Nilvadipine is a safe and effective agent prescribed for patients with both hypertension and chronic major cerebral artery occlusion. In hypertensive patients with high risk of atherosclerosis, nilvadipine may protect LDL cholesterol from in vivo oxidation.
Primary Characteristics
Molecular Weight: 385.4 · Non-proprietary name: Nilvadipine.
Pharmacokinetics
Elimination: plasma half-life is 15-20 hours, renal excretion is via kidneys as inactive metabolites..
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Indications
Nilvadipine is primarily indicated in conditions like Cerebral arteriosclerosis, Hypertension.
Contraindications
Nilvadipine is contraindicated in conditions like Neurological disorders, Hypersensitivity.
Dosage
Nilvadipine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 12 mg | 12 mg | — | oral | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Nilvadipine in overdosage may give rise to further complications which include Osteoporosis , Leukopenia.
The signs and symptoms that are produced after acute overdosage of Nilvadipine are Jaundice , Confusion , Dyspepsia, Jaundice, Anxiety , Chest pain.
Nilvadipine is known to cause more or less tolerable side effects which are usually transient. These include Edema, Flushing, Headache, Palpitation, Sweating .
Warnings / Precautions
Available Brands
Drug Classification
- 1.12.3.2 — Calcium antagonists