Methyltestosterone

Drug #1995

Methyltestosterone is a hormone used to treat men with a testosterone deficiency. It is also used in women to treat breast cancer, breast pain, swelling due to pregnancy, and with the addition of estrogen it can treat symptoms of menopause.

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Primary Characteristics

It is of Synthetic origin and belongs to Anabolic steroid.

Molecular Weight: 302.46 · Solubility in Water: Insoluble · Solubility in Alcohol: Freely soluble · Non-proprietary name: Methyltestosterone.

Molecular structure of Methyltestosterone

Pharmacokinetics

Elimination: it is metabolised via Liver.

Indications

Methyltestosterone is primarily indicated in conditions like Hormone replacement therapy, Hypogonadotrophic hypogonadism, Primary hypogonadism.

Methyltestosterone is also indicated for secondary conditions like Metastatic carcinoma of breast.

Contraindications

Methyltestosterone is contraindicated in conditions like Breast cancer, Pregnancy, Prostate cancer.

Dosage

Methyltestosterone's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
30 mg	30 mg	—	PO	For metastatic breast carcinoma
30 mg	30 mg	—	PO	For androgen replacement therapy.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Major2 interactions

Moderate4 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Methyltestosterone in overdosage may give rise to further complications which include Nausea , Atrophy , Atrophy , GI upsets.

Methyltestosterone is known to cause more or less tolerable side effects which are usually transient. These include Acne, Amenorrhea, Anxiety, Baldness, Depression, Gynecomastia, Headache, Hirsutism , Libido, Oligospermia, Penile erection, Virilization.

Warnings / Precautions

In patients with breast cancer, androgen therapy may cause hypercalcemia by stimulating osteolysis. In this case, the drug should be discontinued. Cholestatic hepatitis and jaundice occur with 17-alpha-alkylandrogens at a relatively low dose. If cholestatic hepatitis with jaundice appears or if liver function tests become abnormal, the androgen should be discontinued and the etiology should be determined. Drug-induced jaundice is reversible when the medication is discontinued. Geriatric patients treated with androgens may be at an increased risk for the development of prostatic hypertrophy and prostatic carcinoma. Edema with or without congestive heart failure may be a serious complication in patients with preexisting cardiac, renal, or hepatic disease. In addition to discontinuation of the drug, diuretic therapy may be required.

Interference in Pathology

Methyltestosterone may interfere in the diagnosis of Liver Function Test (LFT) .

Available Brands

None recorded.

Storage Conditions

Methyltestosterone should be stored Tablets.

Drug Classification

1.18.2 — Androgens