Hydrocodone
Also known as: Dihydrocodeinone, Hydroconum
Hydrocodone is a semi synthetic opioid derived from naturally occuring opiates,codine and thebaine.It is habit forming. It is an orally active narcotic analgesic and antitussive.
Primary Characteristics
Hydrocodone is also known as Dihydrocodeinone, Hydroconum.
It belongs to Codeine, phenonthrene derivative.
Molecular Weight: 299.37 · Non-proprietary name: Hydrocodone.
Pharmacokinetics
Distribution: Hydrocodone has a plasma protein binding is 19 to 45%.
Elimination: it is metabolised via hepatic and intestinal mucusa, plasma half-life is 3.8 hours.
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Indications
Hydrocodone is primarily indicated in conditions like Pain.
Contraindications
Hydrocodone is contraindicated in conditions like Hypersensitivity to the drug.
Dosage
Hydrocodone's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 7.5 mg | 7.5 mg | Every 6h | PO | For irritants cough and modest to severe pain. |
| Paediatric Dosage (20kg) | ||||
| 2.5 mg | 2.5 mg | Every 6h | ||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Hydrocodone in overdosage may give rise to further complications which include Bleeding , Allergic reactions .
The signs and symptoms that are produced after acute overdosage of Hydrocodone are Seizures, Unconsciousness, Coma, Dizziness, Cardiovascular disturbances.
Hydrocodone is known to cause more or less tolerable side effects which are usually transient. These include Anxiety, Constipation , Euphoria, Light headedness, Nausea and vomiting.
Warnings / Precautions
Interference in Pathology
Hydrocodone may interfere in the diagnosis of False-positive test results for urinary 5-hydroxyindoleacetic acid..
Available Brands
Click on a strength to view available brands.
Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.2.2 — Opioid analgesics