Quinestrol

Drug #1919

Quinestrol is synthetic origin used in hormone replacement therapy and occassionally to treat breast cancer and prostate cancer.

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Primary Characteristics

It is of Synthetic origin and belongs to Oestrogen.

Molecular Weight: 364.52 · Non-proprietary name: Quinestrol.

Pharmacokinetics

Elimination: it is metabolised via Hepatic.

Indications

Quinestrol is primarily indicated in conditions like Hormone replacement therapy, Menopausal flushing.

Quinestrol is also indicated for secondary conditions like Breast cancer, Prostate cancer.

Contraindications

Quinestrol is contraindicated in conditions like Vaginal bleeding, Porphyria, Pregnancy.

Dosage

Quinestrol's dosage details are as follows:

Dose	Single Dose	Frequency	Route
Adult Dosage
0 – 0	—	—	PO
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

4 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Quinestrol in overdosage may give rise to further complications which include Systemic lupus erythematosus .

Quinestrol produces potentially life-threatening effects which include Venous thromboembolism. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Quinestrol are Shortness of breadth, Vaginal bleeding.

Quinestrol is known to cause more or less tolerable side effects which are usually transient. These include Bloated feeling, Dizziness, Fluid retention, Nausea and vomiting, Weight gain.

Warnings / Precautions

It should not be given to the patients with active thrombophlebitis or thromboembolic disease, abnormal vaginal bleeding, women with antiphospholipid antibodies, history of endometriosis. when used as HRT, it should be used with caution in diseases which may be excerbated during pregnancy or quinestrol therapy including diabetes, asthma, epilepsy, hypertension, cardiac or renal disease, sickle cell anemia, multiple sclerosis and cholera. It should not be used during lactation.

Available Brands

None recorded.

Storage Conditions

Quinestrol should be stored .

Drug Classification

1.8.2 — Cytotoxic (anti-neoplastic) drugs