Guanabenz
Guanabenz is an antihypertensive drug used to treat high blood pressure. Its derivative Guanabenz Acetate is an alpha agonist used to treat hypertension.
Primary Characteristics
Guanabenz is also known as Guanabenz Acetate.
Molecular Weight: 231.08 · Solubility in Water: sparingly soluble · Solubility in Alcohol: soluble · Non-proprietary name: Guanabenz.
Pharmacokinetics
Distribution: Guanabenz has a plasma protein binding is 90%.
Elimination: plasma half-life is 6 hours, renal excretion is Urine.
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Indications
Guanabenz is primarily indicated in conditions like Hypertension.
Contraindications
Guanabenz is contraindicated in conditions like Allergy, Hypersensitivity.
Dosage
Guanabenz's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 6 mg | 6 mg | Every 12h | oral | Every 1-2 weeks doses up to 32mg twice daily have been used... |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
The signs and symptoms that are produced after acute overdosage of Guanabenz are Bradycardia, Hypotension, Drowsiness, fatigue, Drowsiness, Dizziness, Irritability, Lethargy, Pinpoint pupils, Sleepiness, Slow heartbeat.
Guanabenz is known to cause more or less tolerable side effects which are usually transient. These include Dizziness, Drowsiness, Dry mouth, Headache, Nausea, Weakness.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.12.3.7 — Direct vasodilators