Chloroprocaine

Also known as: Nessacaine

Drug #1896

Chloroprocaine is an anesthetic agent indicated for production of local or regional anesthesia, particularly for oral surgery. Chloroprocaine (like cocaine) has the advantage of constricting blood vessels which reduces bleeding, unlike other local anesthetics like lidocaine.

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Primary Characteristics

Chloroprocaine is also known as Nessacaine.

Pharmacokinetics

None recorded.

Indications

Chloroprocaine is primarily indicated in conditions like Anesthesia, Nerve block.

Chloroprocaine is also indicated for secondary conditions like Analgesic.

Contraindications

Chloroprocaine is contraindicated in conditions like Neurological disorders, Hypersensitivity to the drug.

Dosage

Chloroprocaine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
11 mg/kg	11 mg/kg	Every 24h	IV	With epinephrine.. Not to exceed t max total dose of 800mg.
14 mg/kg	14 mg/kg	Every 24h	IV	Without epinephrine.. Not to exceed t max total dose of 1000mg.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Chloroprocaine in overdosage may give rise to further complications which include CNS stimulation, Convulsions .

Chloroprocaine produces potentially life-threatening effects which include change in cardiac conduction. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Chloroprocaine are Ventricular arrhythmias, Bradycardia, Hypotension, Cardiac arrest, myocardial depression.

Chloroprocaine is known to cause more or less tolerable side effects which are usually transient. These include Blurred vision, Drowsiness, Fever, Itching, Tinnitus.

Warnings / Precautions

The safety and effective use of chloroprocaine depend on proper dosage, correct technique, adequate precautions and readiness for emergencies. Injections should be made slowly, with frequent aspirations before and during the injection to avoid intravascular injection. Local anesthetic injections containing a vasoconstrictor should be used cautiously and in carefully circumscribed quantities in areas of the body supplied by end arteries or having otherwise compromised blood supply. Local anesthetics should also be used with caution in patients with impaired cardiovascular function since they may be less able to compensate for functional changes associated with the prolongation of A-V conduction produced by these drugs. Chloroprocaine should be given to a pregnant woman only if clearly needed.

Available Brands

None recorded.

Storage Conditions

Chloroprocaine should be stored Inj, sol.

Drug Classification

1.1.2 — Local anesthetics