DrugInfoSys

Dimethyl Sulfoxide

Also known as: Methyl sulfoxide, Methyl sulfinyl methane, DMSO

Drug #1858

DMSO is used as a topical analgesic, a vehicle for topical application of pharmaceuticals, as an anti-inflammatory and an antioxidant. FDA has approved the use of DMSO only for palliative treatment of interstitial cystitis. DMSO also use in the veterinary field as a liniment for horses.Use of DMSO in medicine dates from around 1963, when a University of Oregon Medical School team, headed by Stanley Jacob, discovered it could penetrate deeply through the skin and other membranes without damaging them and could carry other compounds deep into a biological system. Some people report an onion- or garlic-like taste after contact with the skin. This is likely due to catabolic processes which reduce DMSO to dimethyl sulfide. Because DMSO increases the rate of absorption of some compounds through organic tissues including skin, it can be used as a drug delivery system.

Primary Characteristics

Dimethyl Sulfoxide is also known as Methyl sulfoxide, Methyl sulfinyl methane, DMSO.

It is of Synthetic origin.

Molecular Weight: 78.13 · Solubility in Water: Soluble · Solubility in Alcohol: Insoluble · Non-proprietary name: Dimethyl Sulfoxide.

Molecular structure of Dimethyl Sulfoxide

Pharmacokinetics

Elimination: renal excretion is Urine.

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Indications

Dimethyl Sulfoxide is primarily indicated in conditions like Palliative treatment of interstitial cystitis.

Dimethyl Sulfoxide is also indicated for secondary conditions like Arthritic pain, Herpes zoster.

Contraindications

Dimethyl Sulfoxide is contraindicated in conditions like Hypersensitivity to any component of product.

Dosage

Dimethyl Sulfoxide's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
0 – 0Intravesical
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Dimethyl Sulfoxide in overdosage may give rise to further complications which include Hypersensitivity reactions , Erythema .

Dimethyl Sulfoxide is known to cause more or less tolerable side effects which are usually transient. These include Burning, Constipation , Diarrhea, Erythema, Headache, Itching, Nausea, Sedation , Vomiting .

Warnings / Precautions

The drug is asssociated with lens changes,therefore assessment of opthalmic function is required.

Interference in Pathology

Dimethyl Sulfoxide may interfere in the diagnosis of Liver Function Test (LFT) .

Available Brands

None recorded.

Storage Conditions

Dimethyl Sulfoxide should be stored .

Drug Classification

  1. 1.12.3.7Direct vasodilators