Pipercuronium
Pipercuronium is a competitive blocking agent. It produces its action by blocking ganglions at motor end plate.It has been used for endotracheal intubation and to provide muscle relaxation in general anesthesia for surgical procedures and to aid mechanical ventilation.
Primary Characteristics
It belongs to Ammonio steroid.
It belongs to Competitive neuromuscular blocker pharmacological group on the basis of mechanism of action.
Molecular Weight: 762.7 · Non-proprietary name: Pipercuronium.
Pharmacokinetics
Elimination: renal excretion is 60%.
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Indications
Pipercuronium is primarily indicated in conditions like Muscle relaxation in surgical anesthesia.
Contraindications
Pipercuronium is contraindicated in conditions like Hypersensitivity.
Dosage
Pipercuronium's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.077 mg/kg | 0.077 mg/kg | — | ||
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Pipercuronium in overdosage may give rise to further complications which include Bradycardia , Hypotension .
The signs and symptoms that are produced after acute overdosage of Pipercuronium are Cardiovascular disturbances, prolonged action for surgery and anestheia.
Pipercuronium is known to cause more or less tolerable side effects which are usually transient. These include Skin rashes, Urticaria.
Warnings / Precautions
Interference in Pathology
Pipercuronium may interfere in the diagnosis of Increased in serum creatinin.
Available Brands
None recorded.
Drug Classification
- 1.12.3.8 — Ganglion blocking drugs