Dexketoprofen

Also known as: Dexketoprofen Trometarnol

Drug #1794

Dexketoprofen is an isomer of ketoprofen. It has been introduced for the short-term relief of mild to moderate pain including dysmenorrhoea.

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Primary Characteristics

Dexketoprofen is also known as Dexketoprofen Trometarnol.

It is of Synthetic origin and belongs to Propionic Acid Derivative.

It belongs to Non steroidal anti inflammatory pharmacological group on the basis of mechanism of action.

Non-proprietary name: Dexketoprofen.

Pharmacokinetics

Distribution: Dexketoprofen has a volume of distribution is 0.215 liters/kg. plasma protein binding is 99%.

Elimination: plasma half-life is 1.65 hour.

Indications

Dexketoprofen is primarily indicated in conditions like Osteoarthritis, Painful musculoskeletal conditions, Primary dysmenorrhea, Toothache.

Contraindications

Dexketoprofen is contraindicated in conditions like Cryptococcal meningitis, see instruction.

Dosage

Dexketoprofen's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
25 mg	25 mg	Every 8h	PO	(Total dose should not exceed 75mg) In case of acute pain drug should be administered at least 30 minutes before meals.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

3 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Dexketoprofen in overdosage may give rise to further complications which include Hepatic damage , Renal damage .

Dexketoprofen is known to cause more or less tolerable side effects which are usually transient. These include Angioedema, Diarrhea, dizziness, Dyspepsia , Fatigue, GI discomfort, Headache, Hypersensitivity reactions, Nausea, nervousness, Pain , Skin rash, Skin RashX, Tinnitus, TinnitusX, Vertigo, VertigoX, Vomiting .

Warnings / Precautions

Dxketoprofen should be used with caution in elderly, during pregnency, and breast feeding and in coagulation defects. Long term use of NSAIDs is associated with reduced female fertility which is reversible on stopping treatment. In patients with renal cardiac and heptic impairment caution is required since NSAIDs may impair renal function.

Available Brands

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Single Ingredient

Tabs

25 mg

Drug Classification

1.2.1.3 — Non steroidal anti-inflammatory drugs (NSAIDs)

Manufacturers

Manufacturers of Dexketoprofen in Pakistan:

S.J.& G