Etoricoxib
Etoricoxib is a non-steroidal anti-inflammatory drug (NSAIDs). Etoricoxib is a selective inhibitor of cyclo-oxygenase-2 and is used for the symptomatic relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and acute gout.
Primary Characteristics
Molecular Weight: 358.84 · Non-proprietary name: Etoricoxib.
Pharmacokinetics
Distribution: Etoricoxib has a plasma protein binding is 92%.
Elimination: it is metabolised via Hepatic CYP extenswely involved, plasma half-life is 22 hrs, renal excretion is 70% & fecal 20%.
Advertisement
Indications
Etoricoxib is primarily indicated in conditions like Acute gout, Ankylosing spondylitis, Muscle relaxation (rapid onset, short duration), Rheumatic arthritis.
Contraindications
Etoricoxib is contraindicated in conditions like Uncontrolled hypertension.
Dosage
Etoricoxib's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 60 mg | 60 mg | Every 24h | PO | For Arthritis, osteoarthritis |
| 90 mg | 90 mg | Every 24h | PO | For Rheumatoid arthritis: |
| 120 mg | 120 mg | Every 24h | PO | For Acute gouty arthritis: |
| 120 mg | 120 mg | Every 24h | PO | ForAnalgesia, Acute pain associated with dental surgery: |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Etoricoxib is known to cause more or less tolerable side effects which are usually transient. These include Angioedema, Depression, Diarrhea, Drowsiness, Fever, GI bleeding, Headache, Hypersensitivity , Nausea, Peptic ulteration, Vertigo, Vomiting .
Warnings / Precautions
Available Brands
Click on a strength to view available brands.
Single Ingredient
Storage Conditions
Drug Classification
- 1.2.1.3 — Non steroidal anti-inflammatory drugs (NSAIDs)