Isoleucine
Isoleucine is a branched-chain amino acid, an essential constituent of the diet. Isoleucine is included in preparations for certain liver disorders, also is used as a dietry suppliment.
Primary Characteristics
It belongs to Amino acid.
Molecular Weight: 131.2 · Solubility in Water: Sparingly soluble · Solubility in Alcohol: Slightly soluble · Non-proprietary name: Isoleucine · pH: 5.5.
Pharmacokinetics
None recorded.
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Indications
Isoleucine is primarily indicated in conditions like Liver diseases, Premedication before surgery.
Contraindications
Isoleucine is contraindicated in conditions like Electrolyte disorder, Hyperammonemia, Hypersensitivity to any component of product.
Dosage
Isoleucine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 675 mg | 675 mg | Every 24h | PO | If one is taking a supplement of isoleucine, he should take it in balance with the other two branched-chain-amino-acids leucine and valine in the formula of 2 mg of leucine and valine for each 1 mg of isoleucine. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Isoleucine is known to cause more or less tolerable side effects which are usually transient. These include Electrolyte imbalance.
Warnings / Precautions
Interference in Pathology
Isoleucine may interfere in the diagnosis of Increased level of Blood urea nitrogen (BUN) concentrations.
Available Brands
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Multi-Ingredient Combinations
Drug Classification
- 1.27 — Vitamins, minerals, tonics, and other susbstances
Manufacturers
Manufacturers of Isoleucine in Pakistan: