Leucine

Drug #1763

Leucine is branched-chain amino acid, an essential constituent of the diet. Leucine is one of the 20 most common amino acid that enhance energy, endurance and aid in muscle tissue recovery and repair. Leucine is included in preparations for certain liver disorders, also is used as a dietry suppliment.

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Primary Characteristics

It is of Natural origin and belongs to Amino acid.

Molecular Weight: 131.2 · Solubility in Water: sparingly soluble · Solubility in Alcohol: Insoluble · Non-proprietary name: Leucine · pH: 5.5.

Pharmacokinetics

None recorded.

Indications

Leucine is primarily indicated in conditions like Liver diseases, Premedication before surgery.

Contraindications

Leucine is contraindicated in conditions like Impaired hepatic function, Impaired renal function.

Dosage

Leucine's dosage details are as follows:

Dose	Single Dose	Frequency	Route
Adult Dosage
16 mg/kg of body weight	16 mg/kg of body weight	Every 24h	PO
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

The signs and symptoms that are produced after acute overdosage of Leucine are Diarrhea, Dermatitis , Pellagra.

Warnings / Precautions

People that exercise a lot, have a low-protein diet, or are seriously trying to build muscle mass should consider leucine supplementation. Leucine is also available in stand-alone supplemental form, but should always be taken together with the other two branched-chain amino acids, isoleucine and valine. People with impaired liver or kidney function should not take isoleucine without first consulting a physician, as large doses of amino acids may aggravate these conditions.

Available Brands

Click on a strength to view available brands.

Multi-Ingredient Combinations

Inf

10.3 g/L 11 g/L 3.76 g/1000ml 4 g/L 4.45 g/L 5.1 g/L 5.48 g/1000ml

Powder

4.06 mg/sachet

Soln

13.6 g/L

Tabs

101 mg

Drug Classification

1.27 — Vitamins, minerals, tonics, and other susbstances

Manufacturers

Manufacturers of Leucine in Pakistan:

B.Braun Mac & Rans Medipak Otsuka Usmanco