Orlistat
Also known as: Tetrahydrolipstatin
Orlistat is a peptic and pancreatic lipase inhibitor that reduces the absorption of fat. Orlistat is used as an adjunct in the treatment of obesity, in those individuals who have a high intake of fats or in the presence of risk factors such as type II diabetes, hypertension and hypercholesterolemia.
Primary Characteristics
Orlistat is also known as Tetrahydrolipstatin.
It is of Synthetic origin.
Molecular Weight: 495.7 · Non-proprietary name: Orlistat.
Pharmacokinetics
None recorded.
Advertisement
Indications
Orlistat is primarily indicated in conditions like Obesity.
Contraindications
Orlistat is contraindicated in conditions like Cholestasis, Pregnancy, Breast feeding, Controlled hypotension in anaesthesia.
Dosage
Orlistat's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 120 mg | 120 mg | Every 8h | PO | Before during or up to 1 hour after meals. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Orlistat is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Anxiety, Faecal urgency, Fatigue, Fecal incontinence, Flatulence, Headache, Hypersensitivity reactions, Liquid oily stools, Menstrual irregularity, Rectal pain.
Warnings / Precautions
Available Brands
Drug Classification
- 1.17.10 — Antiobesity preparations