Zoledronic Acid
A bisphosphonate, which affects bone metabolism. It is adsorbed onto hydroxyapetite cryastals in bone , slowing both their rate of growth and dissolution, and therefore reducing the rate of bone turnover. It reduces bone damage in advanced malignancies involving bone (with calcium and vitamin D supplement), it is also given in hypercalcemia of malignancy.
Primary Characteristics
It is of Synthetic origin and belongs to Biphosphonate.
Non-proprietary name: Zoledronic Acid.
Pharmacokinetics
None recorded.
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Indications
Zoledronic Acid is primarily indicated in conditions like Hypercalcaemia of malignancy, Reduction of bone damage, Skeletal disorder prevention in bone malignancies, Tumour induced hypercalcaemia.
Contraindications
Zoledronic Acid is contraindicated in conditions like Hypersensitivity.
Dosage
None recorded.
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Zoledronic Acid in overdosage may give rise to further complications which include Anemia , Bradycardia , Renal impairment , Increased creatinine , Hypoglycemia, Increase in blood urea .
Zoledronic Acid is known to cause more or less tolerable side effects which are usually transient. These include Anorexia , Arthralgia, Bone pain, Conjunctivitis, Fatigue, Fever, Headache, Myalgia, Nausea, Taste perversion, Thirst, Vomiting .
Available Brands
Drug Classification
- 1.18.14 — Drugs affecting bone metabolism