DrugInfoSys

Natamycin

Also known as: Pimaricin

Drug #1619

Natamycin is a polyene antifungal, one of the currently available ophthalmic antifungal preparations. Natamycin is used locally for the treatment of fungal karatitis, belpharitis, scleritis, mucormycosis, and canaliculitis. Natamycin is also used in the treatment of vaginal trichomoniasis.

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Primary Characteristics

Natamycin is also known as Pimaricin.

It is of Semi Synthetic origin and belongs to Macrolide.

Molecular Weight: 665.75 · Solubility in Water: insoluble · Solubility in Alcohol: soluble · Non-proprietary name: Natamycin · pH: 5.

Molecular structure of Natamycin

Pharmacokinetics

None recorded.

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Indications

Natamycin is primarily indicated in conditions like Blepharitis, Candidiasis, Conjuctivitis, Fungal keratitis.

Natamycin is also indicated for secondary conditions like Intestinal candidiasis, Skin infections, Vaginal infections.

Contraindications

Natamycin is contraindicated in conditions like Hypersensitivity to any component of product.

Dosage

Natamycin's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
10 mg10 mgEvery 24hBuccal (Lozenges)For oral candidiasis.
400 mg400 mg—POPreferably in divided doses. (For intestinal candidiasis)
5 %5 %—Topical (Ophthalmic)For Belpharitis and Conjunctivivtis.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

4 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Natamycin is known to cause more or less tolerable side effects which are usually transient. These include Blurred vision, Eye irritation, Eye Pain , GI disturbance, Hyperemia, Irritation, Photophobia .

Warnings / Precautions

Your doctor should check your progress at regular visits. For some eye infections, these visits may be as often as several times a week. If your symptoms do not improve within 7 to 10 days, or if they become worse, check with your doctor.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Eye Drops
5 %w/v

Storage Conditions

Natamycin should be stored .

Drug Classification

  1. 1.6.3 — Antifungal drugs

Manufacturers

Manufacturers of Natamycin in Pakistan:

JaensOphth-PharmaSanteZinta