Phenolphthalein

Drug #1515

Phenolphthalein is a diphenylmethane stimulant laxative. Phenolphthalein is used in the treatment of constipation and for bowel evacuation before invastigational procedures or surgery.

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Primary Characteristics

It is of Synthetic origin.

Molecular Weight: 318.3 · Solubility in Water: Insoluble · Solubility in Alcohol: 1 in 15 · Non-proprietary name: Phenolphthalein.

Pharmacokinetics

Elimination: renal excretion is 15 %.

Indications

Phenolphthalein is primarily indicated in conditions like Bowel evacuation, Constipation.

Contraindications

Phenolphthalein is contraindicated in conditions like Nausea and vomiting, Abdominal pain, Pregnancy, Lactation.

Dosage

Phenolphthalein's dosage details are as follows:

Dose	Single Dose	Frequency	Route
Adult Dosage
130 mg	130 mg	—	PO
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Moderate1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

The signs and symptoms that are produced after acute overdosage of Phenolphthalein are Diarrhea, Pulmonary edema , Hypoglycemia, Pancreatitis.

Phenolphthalein is known to cause more or less tolerable side effects which are usually transient. These include Abdominal cramps, Colic , Epidermal necrolysis, Eruptions, Erythema multiforme, Skin RashX.

Warnings / Precautions

It should not be given to patients with intestinal obstruction or with undiagnosed abdominal symptoms. It should be used with care in patients with inflammatory bowl disease. Prolong use should be avoided. It should be used with caution (if contain tartrazine) in patients with aspirin hypersensitivity, because may cause allergic reactions (including bronchial asthma). Discontinue use if skin eruption occured.

Available Brands

None recorded.

Storage Conditions

Phenolphthalein should be stored Tab.

Drug Classification

1.17.6 — Laxatives