Ceftibuten
Ceftibuten is an oral third-generationcephalosporin antibiotic. The actions and uses are simlar to cefixime. Ceftibuten is used in the treatment of urinary-tract and respiratory-tract infections.
Primary Characteristics
It is of Semi Synthetic origin and belongs to cephalosporin.
Molecular Weight: 410.4 · Non-proprietary name: Ceftibuten.
Pharmacokinetics
Distribution: Ceftibuten has a plasma protein binding is 66 - 77%.
Elimination: plasma half-life is 2 - 2.3 hr, renal excretion is Main excreted in urine.
Advertisement
Indications
Ceftibuten is primarily indicated in conditions like Respiratory tract infections, Urinary tract infection.
Contraindications
Ceftibuten is contraindicated in conditions like Hypersensitivity to any component of product.
Dosage
Ceftibuten's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 400 mg | 400 mg | Every 24h | PO | On an empty stomach |
| Paediatric Dosage (20kg) | ||||
| 9 mg/kg | 9 mg/kg | Every 24h | children over 6 months of age and weighing 45kg or less | |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
The signs and symptoms that are produced after acute overdosage of Ceftibuten are Seizures, Troubled breathing, Confusion , Weakness .
Ceftibuten is known to cause more or less tolerable side effects which are usually transient. These include Anaphylaxis, Diarrhea, Eosinophilia, Fever, GI disturbance, Headache, Hypersensitivity reactions, Skin RashX, Urticaria.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.6.2.1.3 — Cephalosporins
Manufacturers
Manufacturers of Ceftibuten in Pakistan: