Sevoflurane
Sevoflurane is a volatile halogenated anesthetic. Sevoflurane is administered by inhalation using a calibrated vaporizer. Sevoflurane is employed for induction and maintenance of general anesthesia. It has a rapid onset of action and recovery. It possesses muscle relaxant properties, however having no analgesic properties.
Primary Characteristics
It is of Synthetic origin.
Molecular Weight: 200.1 · Non-proprietary name: Sevoflurane.
Pharmacokinetics
Elimination: it is metabolised via 5 %.
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Indications
Sevoflurane is primarily indicated in conditions like Induction and maintenance of anaesthesia, Induction of anaesthesia, Maintenance of anaesthesia.
Contraindications
Dosage
Sevoflurane's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 5 % v/v | 5 % v/v | — | Inhalation | With oxygen or oxygen and nitrous oxide. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Sevoflurane in overdosage may give rise to further complications which include Hypotension , Myocardial depression , Cardiovascular collapse , Malignant hyperthermia.
Sevoflurane produces potentially life-threatening effects which include Malignant pyrexia. Careful monitoring is needed with proper medical management.
The signs and symptoms that are produced after acute overdosage of Sevoflurane are Depression of vital functions.
Sevoflurane is known to cause more or less tolerable side effects which are usually transient. These include Nausea and vomiting, Shivering .
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.1.1.2 — Inhalational anesthetics