Dihydrotachysterol

Also known as: Vitamin Dy

Drug #1510

Dihydrotachysterol is a form of vitamin D (a fat soluble vitamin). Dihydrotachysterol is used in the treatment and prevention of vitamin deficiency states and in some bone disorders.

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Primary Characteristics

Dihydrotachysterol is also known as Vitamin Dy.

It is of Synthetic origin and belongs to Vitamin D.

Molecular Weight: 398.7 · Solubility in Water: insoluble · Solubility in Alcohol: soluble · Non-proprietary name: Dihydrotachysterol.

Molecular structure of Dihydrotachysterol

Pharmacokinetics

Distribution: Dihydrotachysterol has a plasma protein binding is >99%.

Elimination: it is metabolised via Liver, renal excretion is Biles and feces.

Indications

Dihydrotachysterol is primarily indicated in conditions like Hypocalcaemia, Hypoparathyroidism, Hypophosphataemia, Renal osteodystrophy, Tetany.

Contraindications

Dihydrotachysterol is contraindicated in conditions like Hypercalcaemia, Hypervitaminosis.

Dosage

Dihydrotachysterol's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
0.6 mg	0.6 mg	Every 24h	PO	Maintainance dose
1.6 mg	1.6 mg	—	PO	Initial dose
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Dihydrotachysterol in overdosage may give rise to further complications which include Hypercalcemia , Hyperphosphatemia.

The signs and symptoms that are produced after acute overdosage of Dihydrotachysterol are Headache, Anorexia , Hypercalcemia, Apathy.

Dihydrotachysterol is known to cause more or less tolerable side effects which are usually transient. These include Bone pain, Constipation , Diarrhea, Headache, Lassitude , Metallic taste, Nausea, Polyuria, Somnolence , Sweating , Thirst, Vertigo, Vomiting .

Warnings / Precautions

Dihydrotachysterol should be used with caution in patients with cardiac disease, atherosclerosis or those receiving dogoxin because hypercalcemia with cardiac arrythmias can result. Evaluate vitamin D administration in fortified food, diet and drugs. It may be necessary to limit dietary vitamin D during treatment. If products of vitamin D contain tartrazine may cause allergic reaction (including bronchial asthma) in susceptible individuals, Specially patients with aspirin hypersensitivity. It is classified as pregnancy category C and should be used with caution during pregnancy only if clearly needed.

Interference in Pathology

Dihydrotachysterol may interfere in the diagnosis of Determination of blood calcium level.

Available Brands

None recorded.

Storage Conditions

Dihydrotachysterol should be stored Oral Soln, Caps, Tab.

Drug Classification

1.27 — Vitamins, minerals, tonics, and other susbstances