Sodium Polystyrene Sulphonate

Drug #1505

A dental prophylactic against dental caries. Sodium Polystyrene Sulphonate is effective when included in dentifrices.

Primary Characteristics

It is of Synthetic origin.

Solubility in Water: Insoluble · Solubility in Alcohol: Insoluble · Non-proprietary name: Sodium Polystyrene Sulphonate.

Molecular structure of Sodium Polystyrene Sulphonate

Pharmacokinetics

None recorded.

Indications

Sodium Polystyrene Sulphonate is primarily indicated in conditions like Hyperkalaemia, Oliguria.

Contraindications

Sodium Polystyrene Sulphonate is contraindicated in conditions like Hypokalaemia, Bowel obstruction, Hypersensitivity, Neonates.

Dosage

Sodium Polystyrene Sulphonate's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
37.5 g	37.5 g	—	PO	This is best provided by administering 15 g orally 1 to 4 times a day or 30 to 50 g rectally every 6 hours.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown5 interactions

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Sodium Polystyrene Sulphonate in overdosage may give rise to further complications which include Potassium depletion , Sodium retention, Cardiac arrhythmias, Irritability , Hypokalemia .

The signs and symptoms that are produced after acute overdosage of Sodium Polystyrene Sulphonate are GI concretions, Fecal impaction.

Sodium Polystyrene Sulphonate is known to cause more or less tolerable side effects which are usually transient. These include Anorexia , Confusion, Constipation , Diarrhea, ECG changes, Nausea, Vomiting .

Warnings / Precautions

It should be used with caution in patients with renal failure and with conditions requiring a restricted sodium intake such as heart failure and severe hypertension. Patients receiving sodium polystyrene sulfonate should be monitored for electrolyte disturbances especially hypokalemia.

Available Brands

None recorded.

Storage Conditions

Sodium Polystyrene Sulphonate should be stored Susp.

Drug Classification

1.26.2.1 — Electrolytes (NaCl, KCl & Bicarbonate) and combinations