Paromomycin (Sulphate)
Paromomycin (Sulphate) is an aminoglycoside antibiotic. The antibacterial spectrum is similar to that of neomycin, but is also effcetive against some protozoa, including Leishmania spp., Entamoeba histolytica, and crytosporidium spp.and anthelminitic properties against tape worms. Cross resistance may produce beween paromomycin and kanamycin, neomycin and streptomycin. Paromomycin (Sulphate) is used in the treatment of intestinal protozoal infections, including amoebiasis, cryptosporidiosis, visceral or cutaneous leishmmaniasis and giardiasis. It may also be used in the treatment of tapeworm infection.
Primary Characteristics
It is of Synthetic origin.
Molecular Weight: 615.6 · Solubility in Water: very Soluble · Solubility in Alcohol: Insoluble · Non-proprietary name: Paromomycin (Sulphate) · pH: 5.
Pharmacokinetics
None recorded.
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Indications
Paromomycin (Sulphate) is primarily indicated in conditions like Amoebiasis, Cryptosporidiosis, Giardiasis, Hepatic encephalopathy, Intestinal protozoal infection.
Contraindications
Paromomycin (Sulphate) is contraindicated in conditions like Intestinal obstruction, Hypersensitivity to the drug, Amebiasis.
Dosage
None recorded.
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Paromomycin (Sulphate) in overdosage may give rise to further complications which include Nephrotoxicity , Ototoxicity .
Paromomycin (Sulphate) is known to cause more or less tolerable side effects which are usually transient. These include Diarrhea, Nausea and vomiting.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.6.2.2.5 — Aminoglycosides