Meloxicam
Meloxicam is NSAID (nonsteroidal anti-inflammatory drug) of oxicam family. It has anti-infalmmatory, analgesic and antipyretic properties. Meloxicam is used to reduce fever and inflammation or swelling and to relieve pain. Meloxicam is used to treat pain, swelling and stiffness associated with arthritis..
Primary Characteristics
It is of Synthetic origin and belongs to Dexicamdexicative.
Molecular Weight: 351.4 · pKa: 1.1-4.2 · Solubility in Water: Insoluble · Solubility in Alcohol: Sparingly soluble · Non-proprietary name: Meloxicam.

Pharmacokinetics
Distribution: Meloxicam has a plasma protein binding is 99 %.
Elimination: plasma half-life is 20 hr, renal excretion is 3 % (unchanged).
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Indications
Meloxicam is primarily indicated in conditions like Ankylosing spondylitis, Osteoarthritis, Rheumatoid arthritis.
Contraindications
Meloxicam is contraindicated in conditions like Renal failure, Hepatic failure, Rectal bleeding, Proctitis, Hemorrhoids.
Dosage
Meloxicam's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 11.25 mg | 11.25 mg | Every 24h | PO | daily |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Meloxicam in overdosage may give rise to further complications which include Angioedema , Ulceration , Bleeding , Angioedema , GI perforation.
Meloxicam is known to cause more or less tolerable side effects which are usually transient. These include Dizziness, Headache, Photosensitivity, Pruritus , Rashes , Urticaria.
Warnings / Precautions
Interference in Pathology
Meloxicam may interfere in the diagnosis of Complete blood cell count.
Available Brands
Storage Conditions
Drug Classification
- 1.2.1.3 — Non steroidal anti-inflammatory drugs (NSAIDs)
Manufacturers
Manufacturers of Meloxicam in Pakistan: